Personalized Circuit-targeted Deep Brain Stimulation for Psychiatric Disorders
Description
This presentation will discuss sEEG-guided DBS for personalized target selection, biomarker discovery, and closed-loop strategies to optimize DBS treatment.
Beyond Movement Disorders: Brain Stimulation for the Treatment of Neuropsychiatric Conditions*
Date: September 14, 2025
Time: 11:45 am to 12:45 pm
Track: Interactive Lunch Workshop
Session Description
This session will provide how the brain stimulation techniques have become an integral part of the treatment of movement disorders, made possible by advances in our understanding of the underlying circuitry and thereby greatly expanding the therapeutic possibilities for conditions such as Parkinsonās disease and essential tremor. As our knowledge of brain circuitry underlying other neuropsychiatric illnesses has become more precise, the feasibility of using neurostimulation to treat conditions such as chronic pain, depression, and substance use disorders has come closer to reality. Various techniques, including deep-brain stimulation and low-intensity focused ultrasound, now permit direct neuromodulation targeting circuit abnormalities in brain areas including the ventral striatum and others. Given the frequency with which neurologists encounter the above illnesses, and the importance of the neurologistās involvement in the treatment teams that address them, understanding emerging treatments is critical. In this seminar, Dr. Shirvalkar, Dr. Scangos, and Dr. Moussawi will describe novel work to develop individualized brain stimulation-based treatments for pain, mood, and substance use disorders, respectively. These discussions will include overviews of the techniques themselves and raise other possibilities for their future use.
Learning Objectives
At the conclusion of this session, attendees should be able to:
- Discuss the neurocircuitry of pain, mood, and substance use disorders.
- Discuss the mechanisms of action and potential benefits of various forms of neurostimulation for these disorders.
- Understand how outcome measures for ongoing research studies relate to clinical responses.
Speakers
- (Speaker) Katherine Scangos, MD, PhD
- (Speaker) Prasad Shirvalkar, MD, PhD
- (Speaker) Khaled Moussawi, MD, PhD
Deep Brain Stimulation for Chronic Pain
Description
This presentation will discuss DBS for refractory neuropathic pain syndromes, including closed-loop DBS deployment in five participants.
Speakers
Low-Intensity Focused Ultrasound for Neuropsychiatric Disorders
Description
This presentation will be an overview of low-intensity ultrasound for neuromodulation including the basics, milestones, challenges, and data highlights.