Brandon Holmes, MD, PhD
University of California, San Francisco
Dr. Brandon Holmes is an Assistant Professor of Neurology at the University of California, San Francisco Memory and Aging Center, where he investigates how microglia—the innate immune cells of the CNS—remodel their surface proteome in response to neurodegenerative pathology. His lab integrates mass spectrometry-based proteomics, iPSC-derived systems, and antibody engineering to define novel glial mechanisms driving Alzheimer’s disease. Brandon earned his BA in neuroscience from Oberlin College and completed his MD and PhD at Washington University in St. Louis, where he studied tau propagation. He finished his neurology residency in 2021 and behavioral neurology fellowship in 2023, both at the University of California, San Francisco.