The Hidden Biology of Neuronal Lysosomes in Health and Disease
Description
This presentation will discuss new biological functions of neuronal lysosomes, related to RNA metabolism and local protein synthesis.
Neurodegeneration and Cell Death*
Date: September 14, 2025
Time: 3:30 pm to 5:00 pm
Track: Cross-Cutting Special Interest Group (SIG)
Session Description
This session will present basic and translational science on the topic of mechanisms of neurodegeneration.
Learning Objectives
At the conclusion of this session, attendees should be able to:
- Discuss recent basic research findings related to the mechanisms of neurodegeneration.
- Describe translational research relevant to neurodegeneration.
- Explain how communication between basic and translational scientists, academicians, and industry scientists could be improved.
Speakers
- (Speaker) Michael Ward, MD, PhD
- (Speaker) Nilüfer Ertekin-Taner, MD, PHD, FANA
- (Speaker) Payam Mohassel, MD, FANA
Towards Precision Medicine for Neurodegenerative Diseases
Description
This presentation will describe clinical, neuropathological and etiological heterogeneity of neurodegenerative diseases and their molecular complexity. She will demonstrate examples of how big multi-omics and deep phenotype data can pave the way towards precision therapies and biomarkers for these complex diseases.
Speakers
Serine Palmitoyltransferase (SPT)-related Neurodegenerative and Neurodevelopmental Disorders
Description
This presentation will be an overview of neurodegenerative diseases linked to SPT enzyme, disease pathomechanisms, and potential therapeutic approaches, and future studies.